What are the possible genotypes of the parents?

The genotype of a male with Adrenoleukodystrophy would be Xr  Y.
The genotype of a female with Adrenoleukodystrophy would be Xr Xr
The genotype of a female carrier would be Xr X.
A carrier carries one copy of the altered gene. In females (who have two X chromosomes), a mutation must usually be present in both copies of the gene to cause the disorder. In some cases, however, females who are carriers of a gene mutation on the X chromosome will exhibit signs and symptoms of a disorder beginning in adulthood.
For a female to get Adrenoleukodystrophy, the father must have the disease and the mother must be at least a carrier or have it herself. All a male needs to get Adrenoleukodystrophy is the mother to be a carrier of have it herself. What is interesting about X linked recessive disease is that a father cannot pass on the disease to a son, and a diseased female must have had a diseased father.

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